The word coronavirus did not generate an immediate recognition three years ago unless one was specialized in infectious diseases. However, since the beginning of this worldwide disease, the word elicits apprehension and often confusion. Although both human and animal coronaviruses have been known for quite a while, this particular virus presented with a slew of new features that lead to the severe infections, many lingering symptoms, and millions of deaths. In this discussion we will try to bring up to date information about the most known aspects of this infection. The general structure of the virus and particularly of the parts that stimulate an immune response will be described. We will follow the pathway of virus attachment and entry into the human cells and some of the ways it causes damage to many organs as disparate as the lungs, brain, and blood vessels. We will explore the response of the immune system to the different variants of the virus and how the vaccines fit in that response. We will also have an interactive activity regarding the variants and vaccines that can be used in the classroom.
